中文名称:匹伐他汀钙

中文别名:匹伐他汀钙(标准品);(+)-双{(3R,5S,6E)-7-[2-环丙基-4-(4-氟代苯基)喹啉-3-基]-3,5-二羟基-6-庚烯酸}钙盐 (2:1);匹伐他汀钙;伊伐他汀;匹伐他汀钙API;双{(3R,5S,6E)-7-[2-环丙基-4-(氟代苯基)喹啉-3-苯基]-3,5-二羟基-6-庚烯酸乙酯}钙盐(2:1) 匹伐他汀钙;匹伐他汀钙盐;匹伐他汀钙晶型Ⅰ

英文名称:Pitavastatin calcium

英文别名:Pitavasttin Calcium;Pitavastatin Calcium /NK-104;(+)-Monocalciunbis{(3r,5s,6e)-7-[2-cyclopropyl-4-(4-fluorophenyl-3-quinolyl]-3,5-dihydroxy-6-heptenotate};Pitavastatin calciuM(Livalo);Calcium (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl)-3,5-dihydroxyhept-6-enoate;(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid,calcium salt (2:1);NK-104 Calcium;Pitavastatin CalciuM DISCONTINUED

CAS:147526-32-7

EINECS:807-641-2

分子式:C25H26CaFNO4

分子量:463.56

分子结构:

危险标志:-

风险术语:-

安全术语:避免接触皮肤、避免接触眼睛

物化性质:-

熔点:>138oC (dec.)

相对密度:-

溶解性:-

用途:一种有效的HMG-CoA还原酶抑制剂。Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting Nox. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187.

上游原料:匹伐他汀钙,(E)-7-[2-环丙基-4-(4-氟苯基)-3-喹啉基]-5-羟基-3-氧代-6-庚烯酸乙酯,(4R,6S)-6-[[(1E)-2-环丙基-4-(4-氟苯基)-3-喹啉基]乙烯基]-2,2-二甲基-1,3-二氧六环-4-乙酸叔丁酯

下游产品:匹伐他汀钙